CD14

CD14
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4GLP
Dynodwyr
Cyfenwau	CD14, entrez:929, CD14 molecule
Dynodwyr allanol	OMIM: 158120 HomoloGene: 493 GeneCards: CD14
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • lipopolysaccharide binding • opsonin receptor activity • lipoteichoic acid binding • GO:0001948, GO:0016582 protein binding • peptidoglycan immune receptor activity • lipopeptide binding Cydrannau o'r gell • Golgi apparatus • bilen • Cellbilen • extracellular region • cell surface • lipopolysaccharide receptor complex • anchored component of external side of plasma membrane • membrane raft • anchored component of membrane • endosome membrane • extracellular exosome • external side of plasma membrane • extracellular space • secretory granule membrane Prosesau biolegol • toll-like receptor TLR1:TLR2 signaling pathway • response to bacterium • toll-like receptor 4 signaling pathway • immune system process • cellular response to diacyl bacterial lipopeptide • positive regulation of interferon-gamma production • response to magnesium ion • response to heat • response to electrical stimulus • MyD88-dependent toll-like receptor signaling pathway • receptor-mediated endocytosis • cellular response to triacyl bacterial lipopeptide • TRIF-dependent toll-like receptor signaling pathway • response to tumor necrosis factor • positive regulation of endocytosis • cell surface receptor signaling pathway • response to lipopolysaccharide • cellular response to lipoteichoic acid • ffagocytosis • positive regulation of tumor necrosis factor production • inflammatory response • response to ethanol • I-kappaB kinase/NF-kappaB signaling • toll-like receptor TLR6:TLR2 signaling pathway • cellular response to lipopolysaccharide • response to molecule of bacterial origin • positive regulation of type I interferon production • lipopolysaccharide-mediated signaling pathway • MyD88-independent toll-like receptor signaling pathway • GO:0097285 apoptotic process • innate immune response • GO:0060554, GO:0060555 necroptosis • negative regulation of MyD88-independent toll-like receptor signaling pathway • apoptotic signaling pathway • toll-like receptor signaling pathway • neutrophil degranulation • positive regulation of NIK/NF-kappaB signaling Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	929	n/a
Ensembl	ENSG00000170458	n/a
UniProt	P08571	n/a
RefSeq (mRNA)	NM_001174105 NM_000591 NM_001040021 NM_001174104	n/a
RefSeq (protein)	NP_000582 NP_001035110 NP_001167575 NP_001167576	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CD14 yw CD14 a elwir hefyd yn CD14 molecule a Monocyte differentiation antigen CD14 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 5, band 5q31.3.^[2]

• "The CD14 rs2569190 TT Genotype is Associated with Chronic Periodontitis. ". Genet Test Mol Biomarkers. 2017. PMID 28829191.
• "Interaction of CD14 haplotypes and soluble CD14 on pulmonary function in agricultural workers. ". Respir Res. 2017. PMID 28302109.
• "Association between the -159C/T polymorphism in the promoter region of the CD14 gene and sepsis: a meta-analysis. ". BMC Anesthesiol. 2017. PMID 28122493.
• "Presepsin (sCD14-ST) Is a Novel Marker for Risk Stratification in Cardiac Surgery Patients. ". Anesthesiology. 2017. PMID 28099244.
• "Presepsin for the detection of early-onset sepsis in preterm newborns.". Pediatr Res. 2017. PMID 27925621.