PPID

PPID
Dynodwyr
Cyfenwau	PPID, CYP-40, CYPD, peptidylprolyl isomerase D
Dynodwyr allanol	OMIM: 601753 HomoloGene: 31283 GeneCards: PPID
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • Hsp90 protein binding • heat shock protein binding • transcription factor binding • isomerase activity • peptidyl-prolyl cis-trans isomerase activity • Hsp70 protein binding • GO:0001948, GO:0016582 protein binding • estrogen receptor binding • cyclosporin A binding • unfolded protein binding Cydrannau o'r gell • cytoplasm • nucleolus • cnewyllyn cell • cytosol • nucleoplasm • mitocondria Prosesau biolegol • chaperone-mediated protein folding • cellular response to UV-A • viral release from host cell • lipid droplet organization • GO:1901227 negative regulation of transcription by RNA polymerase II • protein folding • positive regulation of protein secretion • positive regulation of apoptotic process • protein transport • positive regulation of viral genome replication • GO:0097285 apoptotic process • GO:0034622 protein-containing complex assembly • protein peptidyl-prolyl isomerization • protein refolding • negative regulation of apoptotic process • regulation of mitochondrial membrane potential Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5481	n/a
Ensembl	ENSG00000171497	n/a
UniProt	Q08752	n/a
RefSeq (mRNA)	NM_005038	n/a
RefSeq (protein)	NP_005029	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PPID yw PPID a elwir hefyd yn Peptidylprolyl isomerase D (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q32.1.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PPID.

• CYPD
• CYP-40

• "Influence of cyclophilin D protein expression level on endothelial cell oxidative damage resistance. ". Genet Mol Res. 2015. PMID 25966197.
• "Cyclophilin-D: a resident regulator of mitochondrial gene expression. ". FASEB J. 2015. PMID 25837584.
• "Mitochondrial permeability transition in cardiac ischemia-reperfusion: whether cyclophilin D is a viable target for cardioprotection?". Cell Mol Life Sci. 2017. PMID 28378042.
• "The cyclophilin D/Drp1 axis regulates mitochondrial fission contributing to oxidative stress-induced mitochondrial dysfunctions in SH-SY5Y cells. ". Biochem Biophys Res Commun. 2017. PMID 27993675.
• "Cyclophilin D over-expression increases mitochondrial complex III activity and accelerates supercomplex formation.". Arch Biochem Biophys. 2017. PMID 27916505.