PTPRB

PTPRB
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2AHS, 2H02, 2H03, 2H04, 2HC1, 2HC2, 2I3R, 2I3U, 2I4E, 2I4G, 2I4H, 2I5X
Dynodwyr
Cyfenwau	PTPRB, HPTP-BETA, HPTPB, PTPB, R-PTP-BETA, VEPTP, protein tyrosine phosphatase, receptor type B, protein tyrosine phosphatase receptor type B
Dynodwyr allanol	OMIM: 176882 HomoloGene: 2125 GeneCards: PTPRB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein tyrosine phosphatase activity • GO:0098519, GO:0098518 phosphatase activity • transmembrane receptor protein tyrosine phosphatase activity • GO:0001948, GO:0016582 protein binding • phosphoprotein phosphatase activity • hydrolase activity Cydrannau o'r gell • integral component of membrane • receptor complex • integral component of plasma membrane • bilen • Cellbilen • specific granule membrane • tertiary granule membrane Prosesau biolegol • phosphate-containing compound metabolic process • GO:0016576 protein dephosphorylation • angiogenesis • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • peptidyl-tyrosine dephosphorylation • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5787	n/a
Ensembl	ENSG00000127329	n/a
UniProt	P23467	n/a
RefSeq (mRNA)	NM_001109754 NM_001206971 NM_001206972 NM_002837 NM_001330204	n/a
RefSeq (protein)	NP_001103224 NP_001193900 NP_001193901 NP_001317133 NP_002828	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PTPRB yw PTPRB a elwir hefyd yn Protein tyrosine phosphatase, receptor type B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q15.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PTPRB.

• "Protein tyrosine phosphatases and their inhibitors. ". Curr Med Chem. 2005. PMID 15638728.
• "[Molecular portrait of human kidney carcinomas: the gene expression profiling of protein-tyrosine kinases and tyrosine phosphatases which controlled regulatory signals in the cells]. ". Mol Biol (Mosk). 2002. PMID 12068634.
• "Protein tyrosine phosphatase PTPRB regulates Src phosphorylation and tumour progression in NSCLC. ". Clin Exp Pharmacol Physiol. 2016. PMID 27314562.
• "Shear stress-induced redistribution of vascular endothelial-protein-tyrosine phosphatase (VE-PTP) in endothelial cells and its role in cell elongation. ". J Biol Chem. 2014. PMID 24451369.
• "Picomolar concentrations of free zinc(II) ions regulate receptor protein-tyrosine phosphatase β activity.". J Biol Chem. 2012. PMID 22275360.