TCF7

TCF7
Dynodwyr
Cyfenwau	TCF7, TCF-1, transcription factor 7 (T-cell specific, HMG-box), transcription factor 7
Dynodwyr allanol	OMIM: 189908 HomoloGene: 135816 GeneCards: TCF7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • sequence-specific DNA binding • DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001948, GO:0016582 protein binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • beta-catenin binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • transcription regulator complex • cnewyllyn cell • nucleoplasm • nuclear body Prosesau biolegol • cellular response to interleukin-4 • GO:0009373 regulation of transcription, DNA-templated • T cell receptor V(D)J recombination • GO:1901227 negative regulation of transcription by RNA polymerase II • embryonic hindgut morphogenesis • Wnt signaling pathway • transcription, DNA-templated • canonical Wnt signaling pathway involved in negative regulation of apoptotic process • embryonic genitalia morphogenesis • regulation of cell population proliferation • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • neural tube development • embryonic digestive tract morphogenesis • alpha-beta T cell differentiation • beta-catenin-TCF complex assembly • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • canonical Wnt signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6932	n/a
Ensembl	ENSG00000081059	n/a
UniProt	P36402	n/a
RefSeq (mRNA)	NM_001134851 NM_001134852 NM_003202 NM_201632 NM_201634 NM_213648 NM_001346425 NM_001346450 NM_001366502	n/a
RefSeq (protein)	NP_001128323 NP_001333354 NP_001333379 NP_003193 NP_963963 NP_963965 NP_998813 NP_001353431	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TCF7 yw TCF7 a elwir hefyd yn Transcription factor 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5q31.1.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TCF7.

• TCF-1

• "Transcriptional regulation of innate and adaptive lymphocyte lineages. ". Annu Rev Immunol. 2015. PMID 25665079.
• "A WNT/p21 circuit directed by the C-clamp, a sequence-specific DNA binding domain in TCFs. ". Mol Cell Biol. 2012. PMID 22778133.
• "TCF/LEF Transcription Factors: An Update from the Internet Resources. ". Cancers (Basel). 2016. PMID 27447672.
• "Transcriptional Regulatory Network for the Development of Innate Lymphoid Cells. ". Mediators Inflamm. 2015. PMID 26379372.
• "Roles of transcriptional factor 7 in production of inflammatory factors for lung diseases.". J Transl Med. 2015. PMID 26289446.