TUSC3

TUSC3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4M8G, 4M90, 4M91, 4M92
Dynodwyr
Cyfenwau	TUSC3, D8S1992, M33, MRT22, MRT7, N33, OST3A, tumor suppressor candidate 3, MagT2, SLC58A2
Dynodwyr allanol	OMIM: 601385 HomoloGene: 6937 GeneCards: TUSC3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • magnesium ion transmembrane transporter activity • dolichyl-diphosphooligosaccharide-protein glycotransferase activity Cydrannau o'r gell • integral component of membrane • oligosaccharyltransferase complex • Cellbilen • integral component of plasma membrane • endoplasmic reticulum membrane • Reticwlwm endoplasmig • bilen • mitocondria Prosesau biolegol • protein N-linked glycosylation • magnesium ion transport • gwybyddiaeth • transmembrane transport • magnesium ion transmembrane transport • GO:0033578, GO:0033577, GO:0033575, GO:0033576 protein glycosylation • protein N-linked glycosylation via asparagine Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7991	n/a
Ensembl	ENSG00000104723	n/a
UniProt	Q13454	n/a
RefSeq (mRNA)	NM_006765 NM_178234 NM_001356429	n/a
RefSeq (protein)	NP_006756 NP_839952 NP_001343358	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TUSC3 yw TUSC3 a elwir hefyd yn Tumor suppressor candidate 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 8, band 8p22.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TUSC3.

• "Association of TUSC3 gene polymorphisms with non-syndromic mental retardation based on nuclear families in the Qinba mountain area of China. ". Genet Mol Res. 2015. PMID 25966277.
• "Tumor suppressor candidate 3 (TUSC3) prevents the epithelial-to-mesenchymal transition and inhibits tumor growth by modulating the endoplasmic reticulum stress response in ovarian cancer cells. ". Int J Cancer. 2015. PMID 25735931.
• "Decreased Tumor Suppressor Candidate 3 Predicts Poor Prognosis of Patients with Esophageal Squamous Cell Carcinoma. ". Int J Med Sci. 2016. PMID 27994502.
• "Homozygous single base deletion in TUSC3 causes intellectual disability with developmental delay in an Omani family. ". Am J Med Genet A. 2016. PMID 27148795.
• "Decreased TUSC3 Promotes Pancreatic Cancer Proliferation, Invasion and Metastasis.". PLoS One. 2016. PMID 26871953.