Cipla

Cipla Limited
Cipla
FormerlyChemical Industrial & Pharmaceutical Laboratories Ltd. (1935–1984)
TypePublic
BSE: 500087
NSE: CIPLA
NSE NIFTY 50 Constituent
ISININE059A01026
IndustryPharmaceuticals
Founded1935 (88 years ago) (1935)
FounderKhwaja Abdul Hamied
HeadquartersMumbai, Maharashtra, India
Area served
Worldwide
Key people
ProductsPharmaceuticals and diagnostics
RevenueIncrease ₹22,753 crore (US$2.8 billion) (FY23)[1]
Increase ₹5,027 crore (US$630 million) (FY23)[1]
Increase ₹2,802 crore (US$350 million) (FY23)[1]
Total assetsDecrease ₹23,662.56 crore (US$3.0 billion)[2] (2020)
Total equityIncrease ₹15,763.00 crore (US$2.0 billion)[2] (2020)
Number of employees
22,036[3]
SubsidiariesInvagen Pharmaceuticals
Websitewww.cipla.com

Cipla Limited (stylized as Cipla) is an Indian multinational pharmaceutical company, headquartered in Mumbai. Cipla primarily develops medicines to treat respiratory disease, cardiovascular disease, arthritis, diabetes, depression, and many other medical conditions.[4]

Cipla has 47 manufacturing locations across the world and sells its products in 86 countries. It is the third largest drug producer in India.[5][6]

History

In 1935, Cipla was founded by Khwaja Abdul Hamied as the Chemical, Industrial & Pharmaceutical Laboratories in Mumbai.[7][8] In July 1984, the name of the company was changed to 'Cipla Limited'.[8]

Upon Hamied's death in 1972, his son Yusuf Hamied, a Cambridge-educated chemist, took over the company. In 1995, Cipla launched Deferiprone, the world's first oral iron chelator.[7] In 1999, Cipla joined the Indian Pharmaceutical Alliance as a founding member in an effort to promote the development of generic drugs in India.[9][10] During the AIDS epidemic in the early 2000's, Hamied reverse-engineered a three-drug antiretroviral cocktail that was sold for about $12,000 per year to create a cheaper version that sold for $304 per year.[11] This drug was then sold to African charities and governments and "at one time, as much as 40 percent of the AIDS patients in poor countries took Cipla drugs".[11] During the avian flu pandemic in 2006, Cipla was able to reverse engineer the drug Tamiflu and sell it for significantly lower prices.[9] In 2013 Cipla acquired the South African company Cipla-Medpro, kept it as a subsidiary, and changed its name to Cipla Medpro South Africa Limited.[12][13] At the time of the acquisition, Cipla-Medpro had been a distribution partner for Cipla and was South Africa's third-biggest pharmaceutical company.[12] The company had been founded in 2002 and was known as Enaleni Pharmaceuticals Ltd.[14] In 2005, Enaleni bought all the shares of Cipla-Medpro, which had been a joint venture between Cipla and Medpro Pharmaceuticals, a South African generics company,[15] and in 2008 it changed its name to Cipla-Medpro.[16] In September 2023, it was announced Cipla South Africa had acquired the Midrand-headquartered healthcare products manufacturer, Actor Pharma.[17]

In September 2015, Cipla acquired InvaGen Pharmaceuticals and Exelan Pharmaceuticals, two American pharmaceutical companies, for 555 million dollars.[18]

In 2019 Cipla entered digital therapeutics by partnering with Wellthy Therapeutics in India and Brandmed in South Africa.[19]

Products and services

Cipla sells active pharmaceutical ingredients to other manufacturers as well as pharmaceutical and personal care products,[20] including escitalopram oxalate (anti-depressant), lamivudine, and fluticasone propionate.[3] They are the world's largest manufacturer of antiretroviral drugs.[20][21]

In July 2020, the company announced the introduction of Gilead Sciences' Remdesivir under the brand name CIPREMI in India after reaching a voluntary licensing agreement with parent company and DCGI approval for "restricted emergency use" in COVID-19 treatment of critical confirmed patients.[22][23][24]

Operations

Cipla has 34 manufacturing units in 8 locations across India and a presence in over 80 countries.[25][26] Exports accounted for 48% ₹4,948 crore (equivalent to ₹84 billion or US$1.1 billion in 2023) of its revenue for FY 2013–14.[27] Cipla spent ₹517 crore (5.4% of their revenue) in FY 2013–14 on R&D activities.[27] The primary focus areas for R&D were development of new formulations, drug-delivery systems and APIs (active pharmaceutical ingredients). Cipla also cooperates with other enterprises in areas such as consulting, commissioning, engineering, project appraisal, quality control, know-how transfer, support, and plant supply.

As on 31 March 2013, the company had 22,036 employees (out of which 2,455 were women (7.30%) and 23 were employees with disabilities (0.1%)).[3] During the FY 2013–14, the company incurred ₹1,285 crore (equivalent to ₹21 billion or US$260 million in 2023) on employee benefit expenses.[27]

Listings and shareholding

The equity shares of Cipla are listed on the Bombay Stock Exchange,[28] where it is a constituent of the BSE SENSEX index,[29] and the National Stock Exchange of India,[30] where it is a constituent of the CNX Nifty.[31] Its Global Depository Receipts (GDRs) are listed on the Luxembourg Stock Exchange.[27]

As of 31 December 2022, the promoter group, Y. K. Hamied and his family, hold around 33.61% equity shares in Cipla. Individual shareholders hold approximately 14.72% of its shares. SBI Mutual Fund, LIC etc. are the largest non-promoter shareholders in the Company.[32]

Shareholders (as on 31-December-2022) Shareholding[33]
Promoter Group 33.61%
Mutual funds 14.09%
Financial Institution/Banks/Insurance 4.96%
Foreign Institutional Investors (FII) 28.39%
Corporate Bodies 0.53%
Individuals 14.72%
NRIs/OCBs 0.88%
ADRs/GDRs NIL
Others 2.82%
Total 100.00%

Awards and recognitions

  • In 2012, Cipla received the Thomson Reuters India Innovation Award.[34]
  • Cipla won Dun & Bradstreet American Express Corporate Awards in 2006.[35]
  • In 2007, Forbes included Cipla in the 200 'Best under a billion' list of best small Asian companies.[36]
  • In 1980, Cipla won Chemexcil Award for Excellence for exports.[37]
  • In 2015, Cipla stood third in the India's Most Reputed Brands (Pharmaceutical) list,[38] in a study conducted by BlueBytes,[39] a leading Media Analytics firm in association with TRA Research,[40] a brand insights organization (both a part of the Comniscient Group).

Criticism

Emergency contraception

In August 2007, Cipla launched an emergency contraception drug "i-pill" sold over the counter,[41] which was controversial with regard to its being available without a prescription and the large amount of drug contained per dose.[42][43]

Generic drugs

In the late 1960s, Cipla began manufacturing a new, patented drug, propranolol, without the permission of the drug's patent holder, Imperial Chemical Industries; a protest was filed with the Indian government. The CEO of Cipla pressured the government of Indira Gandhi to change India's patent laws to eliminate patents that directly covered drugs, and instead to allow only patents that covered methods to make drugs.[44] so that Cipla could go ahead and produce as many low-priced generic drugs for the poor as possible. Since then Cipla has also produced a low-cost drug to treat HIV, and expanded operations into several developing countries, including African nations, where most HIV and poor patients existed at one time.[45] But the changes made led to criticism of both India's patent laws and Cipla.[46] India reinstated patents on drugs in 2005.[44]

See also

References

  1. ^ a b c Jaiswar, Pooja Sitaram (12 May 2023). "Cipla Q4 results: Consolidated PAT at ₹526 cr, declares dividend". Mint. Retrieved 14 July 2023.
  2. ^ a b "Cipla Consolidated Balance Sheet, Cipla Financial Statement & Accounts". www.moneycontrol.com. Retrieved 28 July 2020.
  3. ^ a b c "Business Responsibility Report 2013-14" (PDF). Cipla. 15 July 2014. Archived from the original (PDF) on 17 March 2015. Retrieved 17 September 2014.
  4. ^ "Know 10 largest Pharmaceutical Companies in India". Edu Dwar. Retrieved 28 July 2023.
  5. ^ "Cipla betting big on digitisation and emerging segments". The Economic Times. Retrieved 6 December 2022.
  6. ^ "Cipla betting big on digitisation and emerging segments". Financial Express. Retrieved 6 December 2022.
  7. ^ a b "About us - History". Cipla Limited. Archived from the original on 27 October 2015. Retrieved 3 November 2014.
  8. ^ a b "Company History - Cipla Ltd". Economic Times. Retrieved 3 November 2013.
  9. ^ a b Dec 22, PTI (22 December 2022). "Indian pharma sector set for 'volume to value leadership' journey in 2023". The Economic Times. ISSN 0013-0389. Retrieved 5 August 2023.
  10. ^ "Introducing IPA- Indian Pharmaceutical Alliance". IPA, Indian Pharmaceutical Alliance. Retrieved 5 August 2023.
  11. ^ a b "Epic saga of Cipla: How a swadeshi Robin Hood took on Big Pharma of the West". The Economic Times. 5 August 2023. ISSN 0013-0389. Retrieved 5 August 2023.
  12. ^ a b Jawani, Lohit (16 July 2013). "Cipla completes acquisition of South Africa's Cipla Medpro". VC Circle. Archived from the original on 15 March 2016. Retrieved 8 September 2016.
  13. ^ "Delists from JSE". Business Day Live. 2013. Retrieved 13 July 2013.
  14. ^ "Enaleni Pharmaceuticals Limited Prospectus 2005". Morningstar. Retrieved 8 September 2016.
  15. ^ Avafia, Tenu; Berger, Jonathan; Hartzenberg, Trudi (2006). "The ability of select sub-Saharan African countries to utilise TRIPs Flexibilities and Competition Law to ensure a sustainable supply of essential medicines: A study of producing and importing countries" (PDF). WHO. Archived from the original (PDF) on 23 January 2014.
  16. ^ Kahn, Tamar (10 September 2008). "South Africa: Enaleni Takes Name of Its Unit Cipla-Medpro". All Africa.
  17. ^ Priyan, Vishnu (5 September 2023). "Cipla to bolster OTC portfolio with acquisition of Actor Pharma". Pharmaceutical Technology. Retrieved 5 September 2023.
  18. ^ JARVIS, LISA (4 September 2006). "Mylan Will Buy Most of Matrix". Chemical & Engineering News Archive. 84 (36): 8. doi:10.1021/cen-v084n036.p008. ISSN 0009-2347.
  19. ^ "Cipla's History". Cipla South Africa. n.d. Retrieved 16 May 2022.
  20. ^ a b "cipla ltd (CIPLA:Natl India)". Business Week. Archived from the original on 6 November 2013. Retrieved 7 November 2013.
  21. ^ "AIDS Healthcare Foundation Campaign Challenges Cipla Over Drug Pricing in India" (Press release). PR Newswire. 8 August 2007. Retrieved 4 November 2013.
  22. ^ "India gives Hetero Labs and Cipla approval to make Gilead's COVID-19 drug". Reuters. 21 June 2020.
  23. ^ "Coronavirus drug: Cipla launches Cipremi's, claims it is the cheapest Remdesivir". The Financial Express. 9 July 2020.
  24. ^ "Coronavirus drug: Cipla ramps up production of antiviral remdesivir amid demand spurt". businesstoday.in.
  25. ^ "Corporate Information: At a Glance". Cipla. Archived from the original on 12 September 2016. Retrieved 6 July 2019.
  26. ^ "Cipla in the pink of health". Business Standard. 25 September 2013. Retrieved 5 November 2013.
  27. ^ a b c d "Annual Report 2013-14" (PDF). Cipla. 22 August 2014. Archived from the original (PDF) on 22 January 2015. Retrieved 17 September 2014.
  28. ^ "Cipla Limited". BSEindia.com. Retrieved 2 November 2013.
  29. ^ "Scripwise Weightages in S&P BSE SENSEX". BSE India. Archived from the original on 1 December 2015. Retrieved 2 November 2013.
  30. ^ "NTPC Limited". NSE India. Retrieved 2 November 2013.
  31. ^ "Download List of CNX Nifty stocks (.csv)". NSE India. Retrieved 2 November 2013.
  32. ^ "StockEdge". web.stockedge.com. Retrieved 25 January 2023.
  33. ^ "Latest CIPLA Shareholding Pattern". Equitymaster. Retrieved 25 January 2023.
  34. ^ DBT, Cipla get Thomson Reuters India innovation awards
  35. ^ "Pharmaceutical sector award". Dun & Bradstreet. 10 September 2006. Archived from the original on 4 November 2013. Retrieved 3 November 2013.
  36. ^ "Asian Paints, Cipla in Forbes list". Economic Times. 17 November 2005. Retrieved 3 November 2013.
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  38. ^ "Lupin, Sun Pharma and Cipla amongst tops most reputed pharma brand list". The Economic Times. timesofindia.com. 17 August 2016. Retrieved 6 July 2019.
  39. ^ "Home". bluebytes.info.
  40. ^ "Home". trustadvisory.info.
  41. ^ "Cipla rises on morning-after pill". Hindustan Times. 5 October 2007. Archived from the original on 5 February 2015. Retrieved 3 November 2013.
  42. ^ "Cipla Launches i-pill". Financial Express. Retrieved 3 November 2013.
  43. ^ "'i-pill' by Cipla draws criticism from experts". Financial Express. 27 October 2007. Retrieved 3 November 2013.
  44. ^ a b "The Treasure of Mumbai". Wired Magazine. December 2006. Retrieved 4 November 2013.
  45. ^ "Heart-warming story of the Hamieds, who set up CIPLA and have been saving lives". National Herald. April 2020. Retrieved 12 April 2020.
  46. ^ "Indian Generic Drug Maker Targets Sad Americans". biohealthinvestor.com. 3 January 2007. Retrieved 4 November 2013.

External links