2WCY
730
109828
ENSG00000112936
ENSMUSG00000079105
P10643
D3YXF5
NM_000587
NM_001243837
NP_000578
NP_001230766
Complement component 7 is a protein involved in the complement system of the innate immune system. C7 is part of the membrane attack complex (MAC) which creates a hole on pathogen surfaces, leading to cell lysis and death.
Its primary task is to bind the C5bC6 complex together. This junction alters the configuration of the protein molecules, exposing a hydrophobic site on C7 that allows the C7 to insert into the phospholipid bilayer of the pathogen.