Tenekteplase

Tenekteplase
Nama sistematis (IUPAC)
Aktivator plasminogen jaringan manusia
Data klinis
Nama dagang TNKase
AHFS/Drugs.com monograph
Data lisensi EMA:pranala
Kat. kehamilan ?
Status hukum ℞ Preskripsi saja
Data farmakokinetik
Ekskresi Hati
Pengenal
Nomor CAS 191588-94-0 YaY
Kode ATC B01AD11
DrugBank DB00031
ChemSpider none N
UNII WGD229O42W YaY
KEGG D02837 YaY
Data kimia
Rumus C2561H3919N747O781S40 

Tenekteplase adalah obat antifibrinolitik yang digunakan untuk mengobati serangan jantung.[1]

Penelitian

Farmakokinetik

Galeri

Referensi

  1. ^ (PDF) http://www.ema.europa.eu/humandocs/PDFs/EPAR/metalyse/065801pt1.pdf.  Tidak memiliki atau tanpa |title= (bantuan)

Bacaan lebih lanjut

  • Gurbel PA, Hayes K, Bliden KP, Yoho J, Tantry US (January 2005). "The platelet-related effects of tenecteplase versus alteplase versus reteplase". Blood Coagulation & Fibrinolysis. 16 (1): 1–7. doi:10.1097/00001721-200501000-00001. PMID 15650539. 
  • Melzer C, Richter C, Rogalla P, Borges AC, Theres H, Baumann G, Laule M (August 2004). "Tenecteplase for the treatment of massive and submassive pulmonary embolism". Journal of Thrombosis and Thrombolysis. 18 (1): 47–50. doi:10.1007/s11239-004-0174-z. PMID 15744554. 
  • Ohman EM, Van de Werf F, Antman EM, Califf RM, de Lemos JA, Gibson CM, et al. (July 2005). "Tenecteplase and tirofiban in ST-segment elevation acute myocardial infarction: results of a randomized trial". American Heart Journal. 150 (1): 79–88. doi:10.1016/j.ahj.2005.01.007. PMID 16084152. 
  • De Luca G, Suryapranata H, Chiariello M (December 2005). "Tenecteplase followed by immediate angioplasty is more effective than tenecteplase alone for people with STEMI. Commentary". Evidence-Based Cardiovascular Medicine. 9 (4): 284–287. doi:10.1016/j.ebcm.2005.09.021. PMID 16380055. 
  • "Primary versus tenecteplase-facilitated percutaneous coronary intervention in patients with ST-segment elevation acute myocardial infarction (ASSENT-4 PCI): randomised trial". Lancet. 367 (9510): 569–578. February 2006. doi:10.1016/S0140-6736(06)68147-6. PMID 16488800. 
  • Bozeman WP, Kleiner DM, Ferguson KL (June 2006). "Empiric tenecteplase is associated with increased return of spontaneous circulation and short term survival in cardiac arrest patients unresponsive to standard interventions". Resuscitation. 69 (3): 399–406. doi:10.1016/j.resuscitation.2005.09.027. PMID 16563599. 
  • Hull JE, Hull MK, Urso JA, Park HA (April 2006). "Tenecteplase in acute lower-leg ischemia: efficacy, dose, and adverse events". Journal of Vascular and Interventional Radiology. 17 (4): 629–636. doi:10.1097/01.RVI.0000202751.74625.79. PMID 16614145. 
  • Peacock M (22 March 2012). "Stroke patients make 'Lazarus-like' recovery". The World Today. 
  • Parsons M, Spratt N, Bivard A, Campbell B, Chung K, Miteff F, et al. (March 2012). "A randomized trial of tenecteplase versus alteplase for acute ischemic stroke". The New England Journal of Medicine. 366 (12): 1099–1107. doi:10.1056/NEJMoa1109842. hdl:1959.13/1039697 alt=Dapat diakses gratis. PMID 22435369. 

Pranala luar

  • Templat:MedlinePlusDrugInfo