Dezoksiribonukleaza I
| Dezoksiribonukleaza I | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.21.1 | ||||||||
| CAS broj | 9003-98-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Dezoksiribonukleaza I (EC 3.1.21.1, pankreasna DNaza, DNaza, timonukleaza, dornaza, dornava, pankreasna dezoksiribonukleaza, pankreasna dornaza, dezoksiribonukleaza (pankreasna), pankreasna DNaza, DNKaza, dezoksiribonukleinska fosfataza, DNaza I, alkalna dezoksiribonukleaza, alkalna DNaza, endodezoksiribonukleaza I, DNK depolimeraza, Escherichia coli endonukleaza I, dezoksiribonukleaza A, DNK endonukleaza, DNK nukleaza) je enzim sa sistematskim imenom '.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Endonukleolitičko razlaganje do 5'-fosfodinukleotidnih i 5'-fosfooligonukleotidnih krajnjih produkata
Ovaj enzim preferentno deluje na dvolančanu DNK.
Reference
- ↑ Privat de Garilhe, M. and Laskowski, M. (1955). „Study of the enzymatic degradation of deoxyribonucleic acid by two different deoxyribonucleodepolymerases”. J. Biol. Chem. 215: 269-276. PMID 14392161.
- ↑ Kunitz, M. (1948). „Isolation of crystalline deoxyribonuclease from beef pancreas”. Science 108: 19-20.
- ↑ Laskowski, M. (1971). „, Sr. Venom exonuclease”. u: Boyer, P.D.. The Enzymes. 4 (3rd izd.). New York: Academic Press. str. 313-328.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Laskowski, M. (1971). „, Sr. Venom exonuclease”. u: Boyer, P.D.. The Enzymes. 4 (3rd izd.). New York: Academic Press. str. 313-328.