Fosfoproteinska fosfataza
| Fosfoproteinska fosfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Identifikatori | |||||||||
| EC broj | 3.1.3.16 | ||||||||
| CAS broj | 9025-75-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Fosfoproteinska fosfataza (EC 3.1.3.16, proteinska fosfataza-1, proteinska fosfataza-2A, proteinska fosfataza-2B, proteinska fosfataza-2C, proteinska D fosfataza, fosfospektrinska fosfataza, kazeinska fosfataza, Aspergillus awamori kiselina proteinska fosfataza, kalcineurin, fosfataza 2A, fosfataza 2B, fosfataza II, fosfataza IB, fosfataza C-II, polikatjonom modulisana (PCM-) fosfataza, fosfopiruvat dehidrogenazna fosfataza, fosfataza SP, dehidrogenazna fosfataza alfa-keto kiselina razgranatog lanca, BCKDH fosfataza, 3-hidroksi 3-metilglutaril koenzimA reduktazna fosfataza, HMG-KoA reduktazna fosfataza, fosfataza H-II, fosfataza III, fosfataza I, proteinska fosfataza, fosfataza IV) je enzim sa sistematskim imenom fosfoprotein fosfohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ova grupa enzima uklanja fosfatne grupe vezane za serin ili treonin sa širokog opsega fosfoproteina.
Reference
- ↑ Deutscher, J., Kessler, U. and Hengstenberg, W. (1985). „Streptococcal phosphoenolpyruvate: sugar phosphotransferase system: purification and characterization of a phosphoprotein phosphatase which hydrolyzes the phosphoryl bond in seryl-phosphorylated histidine-containing protein”. J. Bacteriol. 163: 1203-1209. PMID 2993239.
- ↑ Ingebritsen, T.S. and Cohen, P. (1983). „The protein phosphatases involved in cellular regulation. 1. Classification and substrate specificities”. Eur. J. Biochem. 132: 255-261. PMID 6301824.
- ↑ Sundarajan, T.A. and Sarma, P.S. (1959). „Substrate specificity of phosphoprotein phosphatase from spleen”. Biochem. J. 71: 537-544. PMID 13638262.
- ↑ Tonks, N.K. and Cohen, P. (1984). „The protein phosphatases involved in cellular regulation. Identification of the inhibitor-2 phosphatases in rabbit skeletal muscle”. Eur. J. Biochem. 145: 65-70. PMID 6092084.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.