Glicin N-aciltransferaza
| Glicin N-aciltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.13 | ||||||||
| CAS broj | 9029-95-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Glicin N-aciltransferaza (EC 2.3.1.13, glicinska aciltransferaza, glicin-N-acilaza) je enzim sa sistematskim imenom acil-KoA:glicin N-aciltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acil-KoA + glicin KoA + N-acilglicin
Donori mogu da budu KoA derivati brojnih alifatičnih i aromatičnih kiselina, mada ne fenilacetil-KoA ili (indol-3-il)acetil-KoA.
Reference
- ↑ Nandi, D.L., Lucas, S.V. and Webster, L.T. (1979). „Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization”. J. Biol. Chem. 254: 7230-7237. PMID 457678.
- ↑ Schachter, D. and Taggart, J.V. (1954). „Glycine N-acylase: purification and properties”. J. Biol. Chem. 208: 263-275. PMID 13174534.
- ↑ Webster, L.T., Jr., Siddiqui, U.A., Lucas, S.V., Strong, J.M. and Mieyal, J.J. (1976). „Identification of N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man”. J. Biol. Chem. 251: 3352-3358. PMID 931988.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.