Glutamat-amonijak ligaza
| Glutamat-amonijak ligaza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 6.3.1.2 | ||||||||
| CAS broj | 9023-70-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Glutamat-amonijak ligaza (EC 6.3.1.2, glutaminska sintetaza, glutamilhidroksaminska sintetaza, L-glutaminska sintetaza) je enzim sa sistematskim imenom L-glutamat:amonijak ligaza (formira ADP).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim takođe deluje, manjom brzinom, na 4-metilin-L-glutamat.
Reference
- ↑ Elliott, W.H. (1953). „Isolation of glutamine synthetase and glutamotransferase from green peas”. J. Biol. Chem. 201: 661-672. PMID 13061404.
- ↑ Fry, B.A. (1955). „Glutamine synthesis by Micrococcus pyogenes var. aureus”. Biochem. J. 59: 579-589. PMID 14363150.
- ↑ Lajtha, A., Mela, P. and Waelsch, H. (1953). „Manganese-dependent glutamotransferase”. J. Biol. Chem. 205: 553-564. PMID 13129232.
- ↑ Meister, A. (1962). „Glutamine synthesis”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 6 (2nd izd.). New York: Academic Press. str. 443-468.
- ↑ Woolfolk, C.A., Shapiro, B. and Stadtman, E.R. (1966). „Regulation of glutamine synthetase. I. Purification and properties of glutamine synthetase from Escherichia coli”. Arch. Biochem. Biophys. 116: 177-192. PMID 5336023.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Meister, A. (1962). „Glutamine synthesis”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 6 (2nd izd.). New York: Academic Press. str. 443-468.