Koagulacioni faktor VIIa
| Koagulacioni faktor VIIa | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.4.21.21 | ||||||||
| CAS broj | 65312-43-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Koagulacioni faktor VIIa (EC 3.4.21.21, krvno koagulacioni faktor VIIa, aktivirani krvno koagulacioni faktor VII) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Selektivno razlaganje Arg-Ile veze u faktoru X čime se formira faktor Xa
Ovaj enzim se formira iz prekurzora faktora VII.
Reference
- ^ Nemerson, Y. & Esnouf, M.P. (1973). „Activation of a proteolytic system by a membrane lipoprotein: mechanism of action of tissue factor”. Proc. Natl. Acad. Sci. USA. 70: 310—314. PMID 4510277.
- ^ Davie, E.W., Fujikawa, K., Kurachi, K. and Kisiel, W. (1979). „The role of serine proteases in the blood coagulation cascade”. Adv. Enzymol. 48: 277—318. PMID 367103.
- ^ Jackson, C.M. & Nemerson, Y. (1980). „Blood coagulation”. Annu. Rev. Biochem. 49: 765—811. PMID 6996572.
- ^ Broze, G.J., Jr. & Majerus, P.W. (1981). „Human factor VII”. Methods Enzymol. 80: 228—237.
Literatura
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
- Coagulation+factor+VIIa на US National Library of Medicine Medical Subject Headings (MeSH)
