GTF2B
GTF2B | |
Нинди таксонда бар | H. sapiens[d][1] |
---|---|
Кодирующий ген | GTF2B[d][1] |
Молекулярная функция | ДНК-связывающий[d][2][2], transcription factor binding[d][3], связывание с белками плазмы[d][4][5][6][…], связывание с ионом металла[d][2], thyroid hormone receptor binding[d][7], TBP-class protein binding[d][8][9], RNA polymerase II complex binding[d][10][11], acetyltransferase activity[d][12], promoter-specific chromatin binding[d][12][13], RNA polymerase II core promoter sequence-specific DNA binding[d][9][14][15], zinc ion binding[d][16], histone acetyltransferase activity[d][2], трансферазная активность[d][2], acyltransferase activity[d][2], RNA polymerase II core promoter sequence-specific DNA binding[d][2][17][18][…], RNA polymerase II complex recruiting activity[d][19], transcription factor binding[d][20][19], RNA polymerase II general transcription initiation factor activity[d][21] һәм TBP-class protein binding[d][22][2][19] |
Күзәнәк компоненты | төш[9][9][23][…], нуклеоплазма[d][2], transcription factor TFIID complex[d][21], ядерные тельца[d][2], transcription preinitiation complex[d][8], Хромосома[24], protein-DNA complex[d][5][25][26][…], RNA polymerase II transcription regulator complex[d][27][28][29], Хромосома[2][13], төш[2][2][12][…] һәм transcription preinitiation complex[d][22][19] |
Биологический процесс | ДНК-зависимая регуляция транскрипции[d][2], транскрипция, ДНК-зависимая[d][9], positive regulation of viral transcription[d][30], snRNA transcription by RNA polymerase II[d][2], вирусный процесс[d][2], transcription preinitiation complex assembly[d][2], positive regulation of core promoter binding[d][22], transcription initiation from RNA polymerase II promoter[d][2][29], protein acetylation[d][12], positive regulation by host of viral transcription[d][13], positive regulation of transcription initiation from RNA polymerase II promoter[d][12][17], transcriptional start site selection at RNA polymerase II promoter[d][31], transcription by RNA polymerase II[d][9][32][33][…], RNA polymerase II preinitiation complex assembly[d][34][35][8], RNA polymerase II core complex assembly[d][36][26], histone acetylation[d][2], transcriptional start site selection at RNA polymerase II promoter[d][37][19], DNA-templated transcription, initiation[d][19], transcription by RNA polymerase II[d][2][38][6][…] һәм RNA polymerase II preinitiation complex assembly[d][11][29][22][…] |
GTF2B (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[39][40]
Искәрмәләр
- ↑ 1,0 1,1 UniProt
- ↑ 2,00 2,01 2,02 2,03 2,04 2,05 2,06 2,07 2,08 2,09 2,10 2,11 2,12 2,13 2,14 2,15 2,16 2,17 2,18 2,19 GOA
- ↑ Mahlapuu M. The human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIB // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1998. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.273.36.23335 — PMID:9722567
- ↑ S Lichtsteiner, R Tjian Cloning and properties of the Caenorhabditis elegans TATA-box-binding protein // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 1993. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.90.20.9673 — PMID:8415761
- ↑ 5,0 5,1 Tsai F. T., Sigler P. B. Structural basis of preinitiation complex assembly on human pol II promoters // EMBO J. — NPG, 2000. — ISSN 0261-4189; 1460-2075 — doi:10.1093/EMBOJ/19.1.25 — PMID:10619841
- ↑ 6,0 6,1 Tsai S. Y., Tsai M. J. Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II) // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1992. — ISSN 0021-9258; 1083-351X; 1067-8816 — PMID:1517211
- ↑ Fondell J. D., F Brunel, K Hisatake et al. Unliganded thyroid hormone receptor alpha can target TATA-binding protein for transcriptional repression // Mol. Cell. Biol. — ASM, 1996. — ISSN 0270-7306; 1098-5549; 1067-8824 — doi:10.1128/MCB.16.1.281 — PMID:8524305
- ↑ 8,0 8,1 8,2 M. Sabbah, Kang K. I., L. Tora et al. Oestrogen receptor facilitates the formation of preinitiation complex assembly: involvement of the general transcription factor TFIIB // Biochem. J. — London [etc.]: Portland Press, 1998. — ISSN 0264-6021; 1470-8728 — PMID:9841876
- ↑ 9,0 9,1 9,2 9,3 9,4 9,5 GOA
- ↑ Ha I, Roberts S, Maldonado E et al. Multiple functional domains of human transcription factor IIB: distinct interactions with two general transcription factors and RNA polymerase II. // Genes Dev. — Cold Spring Harbor Laboratory Press, 1993. — ISSN 0890-9369; 1549-5477 — doi:10.1101/GAD.7.6.1021 — PMID:8504927
- ↑ 11,0 11,1 S Malik, Lee D. K., Roeder R. G. Potential RNA polymerase II-induced interactions of transcription factor TFIIB. // Mol. Cell. Biol. — ASM, 1993. — ISSN 0270-7306; 1098-5549; 1067-8824 — doi:10.1128/MCB.13.10.6253 — PMID:8413225
- ↑ 12,0 12,1 12,2 12,3 12,4 Choi C. H., Hiromura M., Usheva A. Transcription factor IIB acetylates itself to regulate transcription // Nature / M. Skipper — NPG, Springer Science+Business Media, 2003. — ISSN 1476-4687; 0028-0836 — doi:10.1038/NATURE01899 — PMID:12931194
- ↑ 13,0 13,1 13,2 Bachvarov D. A new paradigm for transcription factor TFIIB functionality // Sci. Rep. — Macmillan Publishers, NPG, 2014. — ISSN 2045-2322 — doi:10.1038/SREP03664 — PMID:24441171
- ↑ Deng W., Stefan G E Roberts A core promoter element downstream of the TATA box that is recognized by TFIIB. // Genes Dev. — Cold Spring Harbor Laboratory Press, 2005. — ISSN 0890-9369; 1549-5477 — doi:10.1101/GAD.342405 — PMID:16230532
- ↑ Lagrange T. New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB // Genes Dev. — Cold Spring Harbor Laboratory Press, 1998. — ISSN 0890-9369; 1549-5477 — doi:10.1101/GAD.12.1.34 — PMID:9420329
- ↑ Chen H. T., P Legault, J Glushka et al. Structure of a (Cys3His) zinc ribbon, a ubiquitous motif in archaeal and eucaryal transcription // Protein Sci. / B. Matthews — Wiley-Blackwell, 2000. — ISSN 0961-8368; 1469-896X — doi:10.1110/PS.9.9.1743 — PMID:11045620
- ↑ 17,0 17,1 Lagrange T. New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB // Genes Dev. — Cold Spring Harbor Laboratory Press, 1998. — ISSN 0890-9369; 1549-5477 — doi:10.1101/GAD.12.1.34 — PMID:9420329
- ↑ Deng W., Stefan G E Roberts A core promoter element downstream of the TATA box that is recognized by TFIIB. // Genes Dev. — Cold Spring Harbor Laboratory Press, 2005. — ISSN 0890-9369; 1549-5477 — doi:10.1101/GAD.342405 — PMID:16230532
- ↑ 19,0 19,1 19,2 19,3 19,4 19,5 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
- ↑ Mahlapuu M. The human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIB // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1998. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.273.36.23335 — PMID:9722567
- ↑ 21,0 21,1 Nogales E., Tjian R. Near-atomic resolution visualization of human transcription promoter opening // Nature / M. Skipper — NPG, Springer Science+Business Media, 2016. — ISSN 1476-4687; 0028-0836 — doi:10.1038/NATURE17970 — PMID:27193682
- ↑ 22,0 22,1 22,2 22,3 M. Sabbah, Kang K. I., L. Tora et al. Oestrogen receptor facilitates the formation of preinitiation complex assembly: involvement of the general transcription factor TFIIB // Biochem. J. — London [etc.]: Portland Press, 1998. — ISSN 0264-6021; 1470-8728 — PMID:9841876
- ↑ Choi C. H., Hiromura M., Usheva A. Transcription factor IIB acetylates itself to regulate transcription // Nature / M. Skipper — NPG, Springer Science+Business Media, 2003. — ISSN 1476-4687; 0028-0836 — doi:10.1038/NATURE01899 — PMID:12931194
- ↑ Bachvarov D. A new paradigm for transcription factor TFIIB functionality // Sci. Rep. — Macmillan Publishers, NPG, 2014. — ISSN 2045-2322 — doi:10.1038/SREP03664 — PMID:24441171
- ↑ Zhu L., Huang X. Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter-terminator cross-talk // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2017. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M117.811521 — PMID:29158257
- ↑ 26,0 26,1 K Hisatake, Roeder R. G., M Horikoshi Functional dissection of TFIIB domains required for TFIIB-TFIID-promoter complex formation and basal transcription activity // Nature / M. Skipper — NPG, Springer Science+Business Media, 1993. — ISSN 1476-4687; 0028-0836 — doi:10.1038/363744A0 — PMID:8515820
- ↑ L. Zawel, Kumar K. P., D. Reinberg Recycling of the general transcription factors during RNA polymerase II transcription // Genes Dev. — Cold Spring Harbor Laboratory Press, 1995. — ISSN 0890-9369; 1549-5477 — doi:10.1101/GAD.9.12.1479 — PMID:7601352
- ↑ I Ha, Lane W. S., D Reinberg Cloning of a human gene encoding the general transcription initiation factor IIB // Nature / M. Skipper — NPG, Springer Science+Business Media, 1991. — ISSN 1476-4687; 0028-0836 — doi:10.1038/352689A0 — PMID:1876184
- ↑ 29,0 29,1 29,2 Reinberg D, RG R. Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of initiation factors IIB and IIE. // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1987. — ISSN 0021-9258; 1083-351X; 1067-8816 — PMID:3029109
- ↑ Albrecht R. A. Direct interaction of TFIIB and the IE protein of equine herpesvirus 1 is required for maximal trans-activation function // Virology — Elsevier BV, 2003. — 11 p. — ISSN 0042-6822; 1096-0341; 1089-862X — doi:10.1016/J.VIROL.2003.08.017 — PMID:14644612
- ↑ NA H., SG R. The role of human TFIIB in transcription start site selection in vitro and in vivo // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1999. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.274.20.14337 — PMID:10318856
- ↑ Bagby S., Ikura M. Solution structure of the C-terminal core domain of human TFIIB: similarity to cyclin A and interaction with TATA-binding protein // Cell — Cell Press, Elsevier BV, 1995. — ISSN 0092-8674; 1097-4172 — doi:10.1016/0092-8674(95)90483-2 — PMID:7671313
- ↑ I Ha, Lane W. S., D Reinberg Cloning of a human gene encoding the general transcription initiation factor IIB // Nature / M. Skipper — NPG, Springer Science+Business Media, 1991. — ISSN 1476-4687; 0028-0836 — doi:10.1038/352689A0 — PMID:1876184
- ↑ S Malik, Lee D. K., Roeder R. G. Potential RNA polymerase II-induced interactions of transcription factor TFIIB. // Mol. Cell. Biol. — ASM, 1993. — ISSN 0270-7306; 1098-5549; 1067-8824 — doi:10.1128/MCB.13.10.6253 — PMID:8413225
- ↑ Reinberg D, RG R. Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of initiation factors IIB and IIE. // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1987. — ISSN 0021-9258; 1083-351X; 1067-8816 — PMID:3029109
- ↑ Buratowski S, Zhou H Functional domains of transcription factor TFIIB. // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 1993. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.90.12.5633 — PMID:8516312
- ↑ NA H., SG R. The role of human TFIIB in transcription start site selection in vitro and in vivo // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1999. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.274.20.14337 — PMID:10318856
- ↑ Bagby S., Ikura M. Solution structure of the C-terminal core domain of human TFIIB: similarity to cyclin A and interaction with TATA-binding protein // Cell — Cell Press, Elsevier BV, 1995. — ISSN 0092-8674; 1097-4172 — doi:10.1016/0092-8674(95)90483-2 — PMID:7671313
- ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
- ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.
Чыганаклар
- Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
- Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)
Бу — аксым турында мәкалә төпчеге. Сез мәкаләне үзгәртеп һәм мәгълүмат өстәп, Википедия проектына ярдәм итә аласыз. |