Keratin 3
Keratin 3 also known as cytokeratin 3 is a protein that in humans is encoded by the KRT3 gene .[3] [4] Keratin 3 is a type II cytokeratin . It is specifically found in the corneal epithelium together with keratin 12 .
Mutations in the KRT3 encoding this protein have been associated with Meesmanns Corneal Dystrophy .[5]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000186442 - Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Raimondi E, Moralli D, De Carli L, Ceratto N, Balzaretti M, Leube R, Collin C, Romano V (1994). "Assignment of the human cytokeratin 3 gene (KRT3) to 12q12-->q13 by FISH". Cytogenet. Cell Genet . 66 (3): 162–3. doi :10.1159/000133690 . PMID 7510223 .
^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). "New consensus nomenclature for mammalian keratins" . J. Cell Biol . 174 (2): 169–74. doi :10.1083/jcb.200603161 . PMC 2064177 . PMID 16831889 .
^ Irvine AD, Corden LD, Swensson O, Swensson B, Moore JE, Frazer DG, Smith FJ, Knowlton RG, Christophers E, Rochels R, Uitto J, McLean WH (June 1997). "Mutations in cornea-specific keratin K3 or K12 genes cause Meesmann's corneal dystrophy". Nat. Genet . 16 (2): 184–7. doi :10.1038/ng0697-184 . PMID 9171831 . S2CID 24438634 .
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