Doksantrin
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IUPAC ime | |
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(6aS,12bR)-6a,7,8,12b-tetrahidro-6H-hromeno[3,4-c]izohinolin-2,3-diol | |
Identifikatori | |
ATC kod | none |
PubChem | CID 15981509 |
Hemijski podaci | |
Formula | C16H15NO3 |
Molarna masa | 269,295 g/mol |
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Doksantrin je sintetičko jedinjenje koje je potentan i selektivan pun agonist dopaminskog D1 receptora.[1][2]
Reference
- ^ Cueva JP, Giorgioni G, Grubbs RA, Chemel BR, Watts VJ, Nichols DE (2006). „trans-2,3-dihydroxy-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline: synthesis, resolution, and preliminary pharmacological characterization of a new dopamine D1 receptor full agonist”. Journal of Medicinal Chemistry. 49 (23): 6848—57. PMID 17154515. doi:10.1021/jm0604979.
- ^ Przybyla JA, Cueva JP, Chemel BR, Hsu KJ, Riese DJ, McCorvy JD, Chester JA, Nichols DE, Watts VJ (2009). „Comparison of the enantiomers of (±)-doxanthrine, a high efficacy full dopamine D1 receptor agonist, and a reversal of enantioselectivity at D1 versus alpha2C adrenergic receptors”. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 19 (2): 138—46. PMC 2636714
. PMID 19028082. doi:10.1016/j.euroneuro.2008.10.002.
Spoljašnje veze
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