Kanabigerol

Kanabigerol
IUPAC ime
	2-[(2E)-3,7-dimetilokta-2,6-dienil]-5-pentil-benzen-1,3-diol
Identifikatori
CAS broj	25654-31-3
ATC kod	none
PubChem	CID 5315659
ChemSpider	4474921
ChEMBL	CHEMBL497318
Hemijski podaci
Formula	C21H32O2
Molarna masa	316,48 g/mol
	SMILES Oc1cc(cc(O)c1C/C=C(\C)CC\C=C(/C)C)CCCCC; ;
	InChI InChI=1S/C21H32O2/c1-5-6-7-11-18-14-20(22)19(21(23)15-18)13-12-17(4)10-8-9-16(2)3/h9,12,14-15,22-23H,5-8,10-11,13H2,1-4H3/b17-12+ ; Key:QXACEHWTBCFNSA-SFQUDFHCSA-N ;

Kanabigerol (cannabigerol (CBG)) je kanabinoid iz Cannabis roda biljki koji nije psihoaktivan. Kanabigerol je prisutan u visokim koncentracijama u industrijskoj konoplji.

Kanabigerol deluje sa visokim afinitetom kao agonist α₂-adrenergičkog receptora, umereni antagonist 5-HT_1A receptora, i slab antagonist CB₁ receptora.^[1] It also binds to the CB₂ receptor, but whether it acts as an agonist or antagonist at this site is unknown.^[1]

Reference

^ ^а ^б Cascio MG, Gauson LA, Stevenson LA, Ross RA, Pertwee R (2009). „Evidence that the plant cannabinoid cannabigerol is a highly potent alpha(2)-adrenoceptor agonist and moderately potent 5HT receptor antagonist”. British Journal of Pharmacology. 159 (1): 129—141. PMC 2823359 . PMID 20002104. doi:10.1111/j.1476-5381.2009.00515.x.

Molimo Vas, obratite pažnju na važno upozorenje
u vezi sa temama iz oblasti medicine (zdravlja).

[pmid20002104-1] а ^б Cascio MG, Gauson LA, Stevenson LA, Ross RA, Pertwee R (2009). „Evidence that the plant cannabinoid cannabigerol is a highly potent alpha(2)-adrenoceptor agonist and moderately potent 5HT receptor antagonist”. British Journal of Pharmacology. 159 (1): 129—141. PMC 2823359 . PMID 20002104. doi:10.1111/j.1476-5381.2009.00515.x.

[1]