TMC8
TMC8 (Transmembrane channel like 8) هوَ بروتين يُشَفر بواسطة جين TMC8 في الإنسان.[1][2]
الوظيفة
الأهمية السريرية
المراجع
- ^ "Entrez Gene: TMC8 transmembrane channel-like 8". مؤرشف من الأصل في 2010-03-08.
- ^ Ramoz N، Rueda LA، Bouadjar B، Montoya LS، Orth G، Favre M (ديسمبر 2002). "Mutations in two adjacent novel genes are associated with epidermodysplasia verruciformis". Nature Genetics. ج. 32 ع. 4: 579–81. DOI:10.1038/ng1044. PMID:12426567.
قراءة متعمقة
- Olsen JV، Blagoev B، Gnad F، وآخرون (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. ج. 127 ع. 3: 635–48. DOI:10.1016/j.cell.2006.09.026. PMID:17081983.
- Ramoz N، Taïeb A، Rueda LA، وآخرون (2000). "Evidence for a nonallelic heterogeneity of epidermodysplasia verruciformis with two susceptibility loci mapped to chromosome regions 2p21-p24 and 17q25". J. Invest. Dermatol. ج. 114 ع. 6: 1148–53. DOI:10.1046/j.1523-1747.2000.00996.x. PMID:10844558.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
- Keresztes G، Mutai H، Heller S (2003). "TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins". BMC Genomics. ج. 4 ع. 1: 24. DOI:10.1186/1471-2164-4-24. PMC:165604. PMID:12812529.
{استشهاد بدورية محكمة}
: صيانة الاستشهاد: دوي مجاني غير معلم (link) - Strausberg RL، Feingold EA، Grouse LH، وآخرون (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Patel AS، Karagas MR، Pawlita M، وآخرون (2008). "Cutaneous human papillomavirus infection, the EVER2 gene and incidence of squamous cell carcinoma: a case-control study". Int. J. Cancer. ج. 122 ع. 10: 2377–9. DOI:10.1002/ijc.23377. PMC:2705140. PMID:18224692.
- Zavattaro E، Azzimonti B، Mondini M، وآخرون (2008). "Identification of defective Fas function and variation of the perforin gene in an epidermodysplasia verruciformis patient lacking EVER1 and EVER2 mutations". J. Invest. Dermatol. ج. 128 ع. 3: 732–5. DOI:10.1038/sj.jid.5701124. PMID:17960179.
- Lazarczyk M، Pons C، Mendoza JA، وآخرون (2008). "Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses". J. Exp. Med. ج. 205 ع. 1: 35–42. DOI:10.1084/jem.20071311. PMC:2234378. PMID:18158319.
- Kurima K، Yang Y، Sorber K، Griffith AJ (2003). "Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis". Genomics. ج. 82 ع. 3: 300–8. DOI:10.1016/S0888-7543(03)00154-X. PMID:12906855.
- Rady PL، De Oliveira WR، He Q، وآخرون (2007). "Novel homozygous nonsense TMC8 mutation detected in patients with epidermodysplasia verruciformis from a Brazilian family". Br. J. Dermatol. ج. 157 ع. 4: 831–3. DOI:10.1111/j.1365-2133.2007.08123.x. PMID:17711520.